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Journal Articles Current Organic Chemistry Year : 2013

HR-MAS NMR Spectroscopy: A Practical Guide for Natural Samples

Abstract

High Resolution Magic Angle Spinning (HR-MAS) NMR spectroscopy is a versatile technique that provides high resolution NMR data on samples containing solutions, gels and swellable solids. In addition to providing structural information HR-MAS can also be used to investigate interfaces (for example organic structures at the solid-aqueous soil interface), processes such as swelling/flocculation, kinetic transfer between gel/liquid phases, as well as conformation and molecular interactions in situ. As such, HRMAS has potential in a diversity of fields including organic, biological, environmental, and medical research. This manuscript focuses on the application of HR-MAS to intact natural samples. A range of 1D and 2D NMR experiments are reviewed and compared in terms of general performance on a range of samples. Therefore, this practical guide and review should be a useful reference and starting point for those wishing to apply HR-MAS NMR. While this article focuses on natural samples, common key 1D and 2D experiments are considered which may be of interest to readers with diverse research interests.
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Dates and versions

hal-00946143 , version 1 (13-02-2014)

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  • HAL Id : hal-00946143 , version 1

Cite

Hashim Farooq, Ronald Soong, Andre J. Simpson, Denis Courtier-Murias, Wolfgang Bermel, et al.. HR-MAS NMR Spectroscopy: A Practical Guide for Natural Samples. Current Organic Chemistry, 2013, 17 (24), pp.3013-3031. ⟨hal-00946143⟩
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